33 research outputs found
Feedback Control as a Framework for Understanding Tradeoffs in Biology
Control theory arose from a need to control synthetic systems. From
regulating steam engines to tuning radios to devices capable of autonomous
movement, it provided a formal mathematical basis for understanding the role of
feedback in the stability (or change) of dynamical systems. It provides a
framework for understanding any system with feedback regulation, including
biological ones such as regulatory gene networks, cellular metabolic systems,
sensorimotor dynamics of moving animals, and even ecological or evolutionary
dynamics of organisms and populations. Here we focus on four case studies of
the sensorimotor dynamics of animals, each of which involves the application of
principles from control theory to probe stability and feedback in an organism's
response to perturbations. We use examples from aquatic (electric fish station
keeping and jamming avoidance), terrestrial (cockroach wall following) and
aerial environments (flight control in moths) to highlight how one can use
control theory to understand how feedback mechanisms interact with the physical
dynamics of animals to determine their stability and response to sensory inputs
and perturbations. Each case study is cast as a control problem with sensory
input, neural processing, and motor dynamics, the output of which feeds back to
the sensory inputs. Collectively, the interaction of these systems in a closed
loop determines the behavior of the entire system.Comment: Submitted to Integr Comp Bio
Exploring the interplay between Buddhism and career development : a study of highly skilled women workers in Sri Lanka
This article adopts a socio cultural lens to examine the role of Buddhism in highly skilled women workers’ careers in Sri Lanka. While Buddhism enabled women’s career development by giving them strength to cope with difficult situations in work, it also seemed to restrict their agency and constrain their career advancement. Based on our findings, we argue that being perceived as a good Buddhist woman worked as a powerful form of career capital for the respondents in our sample, who used their faith to combat gender disadvantage in their work settings
Electromagnetic compatibility of implantable neurostimulators to RFID emitters
<p>Abstract</p> <p>Background</p> <p>The objective of this study is to investigate electromagnetic compatibility (EMC) of implantable neurostimulators with the emissions from radio frequency identification (RFID) emitters.</p> <p>Methods</p> <p>Six active implantable neurostimulators with lead systems were tested for susceptibility to electromagnetic fields generated by 22 RFID emitters. These medical devices have been approved for marketing in the U.S. for a number of intended uses that include: epilepsy, depression, incontinence, Parkinsonian tremor and pain relief. Each RFID emitter had one of the following carrier frequencies: 125 kHz, 134 kHz, 13.56 MHz, 433 MHz, 915 MHz and 2.45 GHz</p> <p>Results</p> <p>The test results showed the output of one of the implantable neurostimulators was inhibited by 134 kHz RFID emitter at separation distances of 10 cm or less. The output of the same implantable neurostimulator was also inhibited by another 134 kHz RFID emitter at separation distances of 10 cm or less and also showed inconsistent pulsing rate at a separation distance of 15 cm. Both effects occurred during and lasted through out the duration of the exposure.</p> <p>Conclusions</p> <p>The clinical significance of the effects was assessed by a clinician at the U.S. Food and Drug Administration. The effects were determined to be clinically significant only if they occurred for extended period of time. There were no observed effects from the other 5 implantable neurostimulators or during exposures from other RFID emitters.</p
Above- and below-ground vertebrate herbivory may each favour a different subordinate species in an aquatic plant community
At least two distinct trade-offs are thought to facilitate higher diversity in productive plant communities under herbivory. Higher investment in defence and enhanced colonization potential may both correlate with decreased competitive ability in plants. Herbivory may thus promote coexistence of plant species exhibiting divergent life history strategies. How different seasonally tied herbivore assemblages simultaneously affect plant community composition and diversity is, however, largely unknown. Two contrasting types of herbivory can be distinguished in the aquatic vegetation of the shallow lake Lauwersmeer. In summer, predominantly above-ground tissues are eaten, whereas in winter, waterfowl forage on below-ground plant propagules. In a 4-year exclosure study we experimentally separated above-ground herbivory by waterfowl and large fish in summer from below-ground herbivory by Bewick’s swans in winter. We measured the individual and combined effects of both herbivory periods on the composition of the three-species aquatic plant community. Herbivory effect sizes varied considerably from year to year. In 2 years herbivore exclusion in summer reinforced dominance of Potamogeton pectinatus with a concomitant decrease in Potamogeton pusillus, whereas no strong, unequivocal effect was observed in the other 2 years. Winter exclusion, on the other hand, had a negative effect on Zannichellia palustris, but the effect size differed considerably between years. We suggest that the colonization ability of Z. palustris may have enabled this species to be more abundant after reduction of P. pectinatus tuber densities by swans. Evenness decreased due to herbivore exclusion in summer. We conclude that seasonally tied above- and below-ground herbivory may each stimulate different components of a macrophyte community as they each favoured a different subordinate plant species
When Time is Scarce, Timing is Almost Everything: a Comparative Analysis of Fast vs. Slow Insect Locomotor Control
Neveln I, Dallmann C, Sponberg S. When Time is Scarce, Timing is Almost Everything: a Comparative Analysis of Fast vs. Slow Insect Locomotor Control. INTEGRATIVE AND COMPARATIVE BIOLOGY. 2019;59(Suppl. 1):E167
Parution - Social history of medicine
Parution - Social history of medicine Social history of medicine, Volume 24, Issue 2, August 2011 John Slater and María Luz López Terrada Scenes of Mediation: Staging Medicine in the Spanish Interludes Mitchell Lewis Hammond Medical Examination and Poor Relief in Early Modern Germany Gill Newton Infant Mortality Variations, Feeding Practices and Social Status in London between 1550 and 1750 Russell Noyes, Jr. The Transformation of Hypochondriasis in British Medicine, 1680–1830 Zipora Shehory..